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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central vimax penis enlargement product pennis enlargement excersizes pennis enlargement tool penis enlagement before and after pro solution pill penis enlargement patch penis enargement free penile enlargment tip
A dietary supplement is any product that is intended to supplement the diet and that contains at least one of these ingredients: vitamins, minerals, herbs or other botanicals, amino acids, and substances such as enzymes, organ tissues, glandulars, metabolites, or a combination of these ingredients. If you choose to take a dietary supplement, read the supplement label carefully. The label will show how much of a specific vitamin, mineral, botanical, or other is in each dietary supplement. The Food and Drug Administration (FDA) and its Center for Food Safety and Applied Nutrition developed regulations for manufacturers in order to help consumers make informed choices when choosing dietary supplements. Manufacturers are responsible for ensuring that their supplements’ facts label and ingredient list are accurate, that the dietary ingredients are safe, and that the content matches the amount declared on the label. Here is the information that must be on a dietary supplement label: A descriptive name of the product stating that it is a supplement. The name and address of the manufacturer, packer, or distributor. A list of each ingredient contained in the product, listed in the order of predominance by common name or proprietary blend. Ingredients not listed on the facts panel must appear in the other ingredient statement beneath the panel. The net contents of the product. The manufacturer’s suggested serving size. There are no rules that limit a serving size or the amount of a nutrient in any form of dietary supplements. Information on nutrients when they are present in significant levels, such as vitamins A and C, calcium, iron, and sodium, and the percentage Daily Value (% DV) where a reference has been established—this is similar to the nutrients listed in the Nutrition Facts panel on food labels. The Daily Value is essentially the same as the DRI (RDA or AI). All other dietary ingredients present in the product, including botanicals and amino acids—those for which no Daily Value has been established. Multiple and Single Nutrient Supplementation When you choose a general multivitamin and multi-mineral supplement, consider those that offer the full nutrient spectrum, the full range of B-complex vitamins, and antioxidants like beta-carotene and vitamins C and E. A good rule of thumb is to look for daily value percentage ranges from 50 to 150 percent. If a multivitamin has some but not enough of the other vitamins, you can take additional doses of those particular single supplements. Typically, a multivitamin cannot hold enough calcium. In addition to this basic multivitamin and mineral supplement, you may want to take single supplements to boost your health for specific conditions. To be sure that you will not be taking excessive amounts over what is already in the basic supplement, subtract the amount in the basic supplement from the larger amount listed for that single supplement. The difference is the amount of the single supplement you need to add. For example, if your basic supplement provides 200 milligrams (mg) of calcium, you would only take 800 mg of single supplement calcium to receive 1,000 mg of calcium daily. Botanicals Common in High-Potency Supplements Common herbal supplements are sometimes found in the formulation of high-potency or a health-benefit specific multivitamin and mineral supplement. Some herbs are used as specifics and are taken for brief periods or only when symptoms are present. Some herbs are used as tonics and are taken long term, sometimes with short breaks in between. For more information on using herbs and their health benefits, read about them from a reliable source and then discuss them with your health practitioner. Become informed! Here are a few common herbs and their unique properties that you may find in your supplements: Ginkgo Biloba (Ginkgo Biloba) is an antioxidant and improves circulation and memory. It may interact with monoamine oxidase (MAO) inhibitors and blood-thinners and may cause gastrointestinal upset and headaches. Ginseng (Panax ginseng, P. quinquefolius) helps increase energy, and is used as a tonic for fatigue and athletic performance. It may worsen the side effects of stimulants, such as caffeine. Some people experience over-stimulation or stomach upset when taking this herb. Avoid this herb if you have high blood pressure, heart palpitations, insomnia, asthma, or a high fever. Siberian Ginseng or Eleuthero (Eleuthero senticosus) helps increase energy and is used as a tonic for fatigue and stress. Its use may increase the effectiveness and side effects of some antibiotics. Saw Palmetto (Sernoa repens) is effective in the treatment of prostate enlargement or benign prostatic hyperplasia (BPH). Some people experience stomach upset when taking this herb. Echinacea (Echinacea augustifolia, E. pallida, E. Purpurea) is known for its ability to stimulate the body’s defenses against minor vial and bacterial infections such as colds and the flu. Persons allergic to the pollen of other members of the aster family, such as ragweed, may also be allergic to echinacea. Its use may counteract immune-suppressive drugs. Green Tea Extract (Camellia Sinensis plant extract) has antioxidant properties, particularly the phytochemical epigallocatechin gallate (EGCG) and is used as a tonic. Milk Thistle (Silybum marianum) is considered a liver protector and healer and is used as a liver tonic. Black Cohosh (Cimicifuga racemosa) has been shown to be effective for premenstrual and menopausal symptoms, such as hot flashes. It may cause stomach upset. Pregnant and nursing women should avoid using this herb. Copyright 2006. Mary El-Baz. All rights reserved. pennis enlargement doctor penis enlagement technique bottle vimax pills enlargement manhattan pnis surgeon male pennis enlargement buy place vig rx vimax herbal penis enlargement penis enlargement photo enlagement erection penis pill vimax
Men take penis enlargement pills because as they get older, their libido, sex drive, erection strength, fertility and other aspects of their sexuality tend to start dropping a few levels. This is exactly why there are so many male enhancement companies selling their penis enlargement pills which are guaranteed to save the day. With all these companies around promoting their male enhancement and penis enlargement pills, you now have a ton of options when trying to find something to work for you. What are the best penis enlargement pills? Well what it really comes down to is what’s inside the company’s “amazing” formula and if it contains a rich blend of the right ingredients. A good penis enlargement pill company will never hide its ingredients from you and also it doesn’t use ingredients like Yohimbe, which are banned or not recommended by the FDA. After having tried various penis enlargement pills, I have found that some of the most effective and best pills have the following high quality ingredients. Zinc (glutonate) aids in creating healthy and better quality sperm. It is also helps balance your testosterone. Zinc, in the form of zinc gluconate, is more easily used by the body than other forms. Arjuna is used mainly in cardiovascular health, Arjuna is an important part of a healthy sexual lifestyle. It regulates blood pressure and heart rate, and works to pace the body, which has been seen to be very helpful in curing common problems like premature ejaculation during sex. Musli is found in the South-Eastern part of India. It is a safe, natural aphrodisiac used in Ayurvedic medicine and also Chinese traditional medicine. It has been said by some to be the natural alternative to Viagra and is essential for it's many beneficial qualities. Shatavari acts as a full treatment on its own, Shatarvi has been shown to help males suffering from erectile dysfunction and impotence. Overall, it has a calming affect on the body, balancing out body weight, decreasing anxiety and promoting healthy sleep. Apigenin is a citrus herb used primarily in preventing and treating cancer. Amla is the world's richest source of Vitamin C. Bioflavonoids, such as apigenin, are thought to work well together with Vitamin C (Amla) in the maintenance of blood vessel health. This pair helps keep your sexual organ healthy and functioning properly over the long term. So you see, some pills can be worth your time. A good penis enlargement pill will contain some if not all of these high quality ingredients. Herbal pills like the ones for penis enlargement and male enhancement are a completely natural alternative to prescription medicine and have no side effect. I recommend combining the penis enlargement pills with natural enlargement exercises because when done properly these exercises can really help you see bigger and faster results from natural penis enlargement. penile enlargement operation homemade penis enargement natural penis enlagement manual pnis enlargement best enlargement exercise penis free penis enlargement tip home penis enlagement buy penile enlargement pills enlagement erection penis pill vimax
Using a condom is the best way to avoid becoming infected with HIV (the AIDs virus) and other STDs (Sexually Transmitted Diseases). Here are some things you should know about condoms and STDs. Some facts about sexually transmitted diseases Having sexual intercourse with an infected person is the most common way of becoming infected. A large percentage of those infected are teenagers or young adults. Your risk of becoming infected increases when you change sexual partners. There may be no symptoms soon after infection. Symptoms may be easily confused with other illnesses. Symptoms of STDs - See a doctor if you have any of these Pain or burning during urination and/or intercourse. Discharge from the vagina, penis and/or rectum. Pain in the abdomen (women), testicles (men), and buttocks and legs (both). Sores, Blisters, warts, rash, swelling in the genital area, or mouth. Fever headache, aching muscles, swollen glands. Who should use a condom to prevent infection from STDs? Anyone who takes part in risky sexual activity should wear a condom. The highest risk comes from having intercourse --vaginal, anal or oral -- with a person who has a sexually transmitted disease. If you have sex with an infected person, you're taking a big chance. The best defence is to never have sex with an infected person. If you decide to have sex with an infected partner, you should ALWAYS use a condom from start to finish, every time. Will using a condom guarantee I won't get a sexually transmitted disease? Most experts agree that the risk of getting AIDS and other STDs can be greatly reduced if a condom is used properly. But you can never be 100% guaranteed not to become infected. And certainly condoms are much better than any other contraceptive alternative. How does a condom protect against sexually transmitted diseases? A condom is a barrier that prevents the transfer of bodily fluids between partners. If no condom is used, the germs can pass from the infected partner to the uninfected partner. How do I choose the best condom to prevent STDs? Read the label. Tests have shown that latex condoms can prevent the passage of STDs while natural (lambskin) condoms may not do this. The package should say that the condoms are effective in preventing disease. If the package doesn't say anything about preventing disease, the condoms may not provide the protection you want, even though they may be the most expensive ones you can buy. Novelty condoms will not say anything about either disease prevention or pregnancy prevention on the package. They are intended only for sexual stimulation, not protection. Condoms which do not cover the entire penis are not labeled for disease prevention and should not be used for this purpose. For proper protection, a condom must unroll to cover the entire penis. This is another good reason to read the label carefully. What kind of safeguards do condom manufacturers have in place? All brand name condoms are subjected to rigorous quality control tests at every stage of the manufacturing process. In the US, each condom is electronically tested for holes and defects. Samples are taken from each lot and visually examined using a water leak test. In this test the samples are filled with 300 ml of water and suspended for 3 minutes. Samples from each lot are also subjected to an Air Inflation Test. This involves filling the test condoms with air until they reach the bursting point. They typically will hold about 40 liters of air -- the equivalent of 9 gallons of water! Other samples are checked for size and thickness, some are tested to destruction for physical strength, and still others are artificially aged by applying high temperatures to ensure that they will retain their quality well beyond their 5 year product life. Are condoms from vending machines any good? Using condoms from a vending machine may be risky. The fact is you can't be sure you are getting a quality latex condom from a vending machine. It may also not be designed (and labelled) for disease prevention, so you may not get the maximum protection. If the vending machine condom contains a spermicide you have no way of knowing if it is outdated. And if the machine is exposed to extreme temperatures and direct sunlight these can easily have an adverse effect on the condoms. Where should I buy condoms? The best advice is to buy from a reputable source that deals only in name brand products. If you are buying online, make sure the website features a broad range of name brand condoms, contains helpful information about condom alternatives, and is reachable by phone so you can talk to a real person. discount vig rx penile enlargement supplement enlargement free penis pill sample penis enlagement excercises vimax penis enlargement forum enlagement free penis pills sample real penis enargement prosolution pnis enlargement pills enlagement erection penis pill vimax
Franchising Trade Journals do not do well, because today with all the industry regulations only about 1800 active franchise actually exist in the US. Down sharply over the past five years. Why? Over-regulation. Now you have a Bank Cooperative, which owns a company that collect data, FranData of Uniform Franchise Offering Circulars, which are the industries required disclosure documents to new franchise buyers. The company sells it to attorneys and to competitors of which many probably are financed through that bank. My God can this be real. Then they work with industry Trade Journals to do Top 50 franchises lists, but to be qualified to be reviewed they of course wish to see your UFOC; Uniform Franchise Offering Circular. So what is the deal with this purported 50 Fastest New Franchise List? Is it real? Does it matter if it is? After all once a Franchisor decides to participate they have just given their life's work to someone who will sell the data including the names addresses and phone numbers of each and every one of your franchisees to your competitors or to franchise industry salesmen who will never stop harassing you or your company and to the over seas competitors who want to come into this country and take you customers and end use customers of your franchise families income. You think this is acceptable? It is unbelievable to think that this is acceptable, in a time when Accounting Firms and Agencies cannot advise and audit or a time when the NYSE is splitting up it's executive and regulating boards. This whole thing smells of Conflict of interest, anti-trust laws, misrepresentation of intent. Meanwhile the SBA, a government agency, paid by us is paying this company or has given them an exclusive to collect this data for their SBA registry of franchising companies to streamline loan application process times? Holly conflict of interest; can you believe that the industry has there penis so far up the regulating agencies rear end that they allow this? Then a lady who called our company had the nerve to ask us to participate with them in a survey, so she can help us get more publicity? No; so their company can give away our information to those companies who cannot compete with us head on in the market place, because they are either to incompetent or too lazy to offer better service and lower prices to the consumer. Instead they are willing to pay for all our secrets via a group financed by government contracts at the SBA, which is really involved in industry spying? Wow, for an agency like the SBA which is suppose to help people in achieving their American Dream, they have allowed and exclusive contract to a company that wants to put the screws to the next Ray Kroc, up and coming franchise concept? Pathetic, typical Washington, "It's who you know and who you BLOW" attitude, literally. You can bet that http://www.Franchising.org is going to get to the bottom of this, meanwhile if you are an up and coming franchisor and you want to succeed, then realize who you are dealing with before you allow the important data that makes your business possible out of your sight. Franchise Buyers must be screened carefully, do not hand over your information, data, financial audit, or profile without weighing the benefits first. Be sure to ask questions of these companies who claim to be helping you in some way? Yah sure, they are going out of their way to help you? Since when has anyone besides a new franchisor; ever done that in your life? Since when has someone gone out of their way to assist you in building your franchise company? What we see here is an undermining of the entire Friedman Economic Model, which dictates free markets, which is run by a company which profits from screwing over the little guy. Last time I checked it was new smaller businesses and expanding businesses, which provided jobs. Not the government or attorneys, speaking of which wasn’t it great watching that lawyer hide behind the tree the other day trying not to be shot buy a guy he ripped off; I think that happened at a California court house last year? In my opinion FranData a subsidiary of the National Bank Cooperative is violating the intent if not the letter of the law as it relates to anti-trust. And it is our opinion that only a D.C. Company could get way with such a conflict of interest working in cahoots with a government agency, which literally gives out money. Have you seen the fall out rates of SBA loans? It is also our opinion that we were lied to by FranData for them to secure more information from our company to give, actually sell, to our competitors. What started out as a nice contract for a Black African American businessman has been manipulated and then sold to a Bank Cooperative, which uses this data through a subsidiary to profit of the sale of said data to competitors. Does this affect our team? Our Company, the franchise business I have been working on for 27 years? Well, it could if we give our data to these people to sell online. But still these companies buying the data will see we do not take prisoners in the marketplace. However for a small franchisor starting out, it could spell disaster. Every time we see these things, we are more resolved to get out there and kick ass against those who manipulate the system, break the law or think they can take the easy way out to compete with us. My advice for this new franchise entrepreneur, Watch Out, things are not as they appear and it is politics as usual in the Belt Way. Think about it. Additional thoughts on this subject www.parthe.net/_fr0202/00000019.htm www.parthe.net/_fr0202/0000001d.htm www.parthe.net/_fr0202/00000013.htm www.parthe.net/_fr0202/00000023.htm www.carwashguys.com/073102_1.shtml